Rochelle D. Schwartz-Bloom
Professor in Pharmacology & Cancer Biology
Dr. Schwartz-Bloom is a co-principal investigator for the National Science Foundation Phase II Noyce Fellowship program.
The Schwartz-Bloom laboratory has completed 18 years of research investigating novel pharmacologic approaches to prevent neuronal death caused by cerebral ischemia associated with cardiac arrest and stroke. The group studied how GABA neurotransmission dysfunction contributes to the death of hippocampal neurons after ischemia in vivo or in vitro. Dr. Schwartz-Bloom’s research program continues now exclusively in science education, which she started in 1996. With funds provided by the Duke Provost in 2007, Dr. Schwartz-Bloom established Duke Center for Science Education, an umbrella for all Duke-related activities in science education. She coordinates Duke faculty and student interests in curriculum development, research, and outreach activities in science education for the K-16 grades. Dr. Schwartz-Bloom also directs RISE (Raising Interest in Science Education, http://sites.duke.edu/rise), an office within the Department of Pharmacology and Cancer Biology, where she develops and provides novel science education curricular materials in the area of pharmacology to the K-12 and college community. One of the major programs that she developed is the Pharmacology Education Partnership (http://sites.duke.edu/thepepproject), a series of pharmacology- and drug abuse-related science education modules for high school biology and chemistry students. Testing of over 15,000 high school students has revealed that student performance in biology and chemistry improves when they use the pharmacology curriculum developed by her team. Dr. Schwartz-Bloom provides several opportunities for Duke Pharmacology graduate students and post-doctoral fellows to obtain experience in teaching.
- Ph.D., Georgetown University 1983
Clarke, PB, Schwartz, RD, Paul, SM, Pert, CB, and Pert, A. "Nicotinic binding in rat brain: autoradiographic comparison of [3H]acetylcholine, [3H]nicotine, and [125I]-alpha-bungarotoxin." J Neurosci 5.5 (May 1985): 1307-1315.
Schwartz, RD, Skolnick, P, Hollingsworth, EB, and Paul, SM. "Barbiturate and picrotoxin-sensitive chloride efflux in rat cerebral cortical synaptoneurosomes." FEBS Lett 175.1 (September 17, 1984): 193-196.
Rainbow, TC, Schwartz, RD, Parsons, B, and Kellar, KJ. "Quantitative autoradiography of nicotinic [3H]acetylcholine binding sites in rat brain." Neurosci Lett 50.1-3 (September 7, 1984): 193-196.
Schwartz, RD, Lehmann, J, and Kellar, KJ. "Presynaptic nicotinic cholinergic receptors labeled by [3H]acetylcholine on catecholamine and serotonin axons in brain." J Neurochem 42.5 (May 1984): 1495-1498.
Schwartz, RD, Taylor, RL, and Kellar, KJ. "Muscarinic cholinergic receptors labeled by [3H]acetylcholine in rat brain." Federation Proceedings 43.3 (1984): no.-1647.
Schwartz, RD, and Kellar, KJ. "[3H]acetylcholine binding sites in brain. Effect of disulfide bond modification." Mol Pharmacol 24.3 (November 1983): 387-391.
Schwartz, RD, and Kellar, KJ. "Nicotinic cholinergic receptor binding sites in the brain: regulation in vivo." Science 220.4593 (April 8, 1983): 214-216.
Schwartz, RD, and Kellar, KJ. "[3H]Acetylcholine binding sites in brain. Effect of disulfide bond modification." Molecular Pharmacology 24.3 (1983): 387-391.
Schwartz, RD, McGee, R, and Kellar, KJ. "Nicotinic cholinergic receptors labeled by [3H]acetylcholine in rat brain." Mol Pharmacol 22.1 (July 1982): 56-62.
Schwartz, RD, Moerschbaecher, JM, Thompson, DM, and Kellar, KJ. "Effects of chronic phencyclidine on fixed-ratio responding: no relation to neurotransmitter receptor binding in rat cerebral cortex." Pharmacol Biochem Behav 16.4 (April 1982): 647-652.