Rochelle D. Schwartz-Bloom
Professor in Pharmacology & Cancer Biology
Dr. Schwartz-Bloom is a co-principal investigator for the National Science Foundation Phase II Noyce Fellowship program.
The Schwartz-Bloom laboratory has completed 18 years of research investigating novel pharmacologic approaches to prevent neuronal death caused by cerebral ischemia associated with cardiac arrest and stroke. The group studied how GABA neurotransmission dysfunction contributes to the death of hippocampal neurons after ischemia in vivo or in vitro. Dr. Schwartz-Bloom’s research program continues now exclusively in science education, which she started in 1996. With funds provided by the Duke Provost in 2007, Dr. Schwartz-Bloom established Duke Center for Science Education, an umbrella for all Duke-related activities in science education. She coordinates Duke faculty and student interests in curriculum development, research, and outreach activities in science education for the K-16 grades. Dr. Schwartz-Bloom also directs RISE (Raising Interest in Science Education, http://sites.duke.edu/rise), an office within the Department of Pharmacology and Cancer Biology, where she develops and provides novel science education curricular materials in the area of pharmacology to the K-12 and college community. One of the major programs that she developed is the Pharmacology Education Partnership (http://sites.duke.edu/thepepproject), a series of pharmacology- and drug abuse-related science education modules for high school biology and chemistry students. Testing of over 15,000 high school students has revealed that student performance in biology and chemistry improves when they use the pharmacology curriculum developed by her team. Dr. Schwartz-Bloom provides several opportunities for Duke Pharmacology graduate students and post-doctoral fellows to obtain experience in teaching.
- Ph.D., Georgetown University 1983
Schwartz, RD. "Autoradiographic distribution of high affinity muscarinic and nicotinic cholinergic receptors labeled with [3H]acetylcholine in rat brain." Life Sci 38.23 (June 9, 1986): 2111-2119.
Suzdak, PD, Schwartz, RD, Skolnick, P, and Paul, SM. "Ethanol stimulates gamma-aminobutyric acid receptor-mediated chloride transport in rat brain synaptoneurosomes." Proc Natl Acad Sci U S A 83.11 (June 1986): 4071-4075.
Majewska, MD, Harrison, NL, Schwartz, RD, Barker, JL, and Paul, SM. "Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor." Science 232.4753 (May 23, 1986): 1004-1007.
Schwartz, RD, Skolnick, P, Seale, TW, and Paul, SM. "Demonstration of GABA/barbiturate-receptor-mediated chloride transport in rat brain synaptoneurosomes: a functional assay of GABA receptor-effector coupling." Adv Biochem Psychopharmacol 41 (1986): 33-49.
Schwartz, RD, Paul, SM, and Majewska, MD. "Factors modulating the sensitivity of the GABA receptor-gated chloride ion channel." Clin Neuropharmacol 9 Suppl 4 (1986): 389-391.
Schwartz, RD, Suzdak, PD, and Paul, SM. "γ-Aminobutyric acid (GABA)- and barbiturate-mediated 36Cl-uptake in rat brain synaptoneurosomes: Evidence for rapid desensitization of the GABA receptor-coupled chloride ion channel." Molecular Pharmacology 30.5 (1986): 419-426.
Schwartz, RD, Jackson, JA, Weigert, D, Skolnick, P, and Paul, SM. "Characterization of barbiturate-stimulated chloride efflux from rat brain synaptoneurosomes." J Neurosci 5.11 (November 1985): 2963-2970.
Schwartz, RD, and Kellar, KJ. "In vivo regulation of [3H]acetylcholine recognition sites in brain by nicotinic cholinergic drugs." J Neurochem 45.2 (August 1985): 427-433.
Schwartz, RD, Thomas, JW, Kempner, ES, Skolnick, P, and Paul, SM. "Radiation inactivation studies of the benzodiazepine/gamma-aminobutyric acid/chloride ionophore receptor complex." J Neurochem 45.1 (July 1985): 108-115.
Kellar, KJ, Martino, AM, Hall, DP, Schwartz, RD, and Taylor, RL. "High-affinity binding of [3H]acetylcholine to muscarinic cholinergic receptors." J Neurosci 5.6 (June 1985): 1577-1582.