Rochelle D. Schwartz-Bloom
Professor in the Program in Education
Dr. Schwartz-Bloom is a co-principal investigator for the National Science Foundation Phase II Noyce Fellowship program.
The Schwartz-Bloom laboratory has completed 18 years of research investigating novel pharmacologic approaches to prevent neuronal death caused by cerebral ischemia associated with cardiac arrest and stroke. The group studied how GABA neurotransmission dysfunction contributes to the death of hippocampal neurons after ischemia in vivo or in vitro. Dr. Schwartz-Bloom’s research program continues now exclusively in science education, which she started in 1996. With funds provided by the Duke Provost in 2007, Dr. Schwartz-Bloom established Duke Center for Science Education, an umbrella for all Duke-related activities in science education. She coordinates Duke faculty and student interests in curriculum development, research, and outreach activities in science education for the K-16 grades. Dr. Schwartz-Bloom also directs RISE (Raising Interest in Science Education, http://sites.duke.edu/rise), an office within the Department of Pharmacology and Cancer Biology, where she develops and provides novel science education curricular materials in the area of pharmacology to the K-12 and college community. One of the major programs that she developed is the Pharmacology Education Partnership (http://sites.duke.edu/thepepproject), a series of pharmacology- and drug abuse-related science education modules for high school biology and chemistry students. Testing of over 15,000 high school students has revealed that student performance in biology and chemistry improves when they use the pharmacology curriculum developed by her team. Dr. Schwartz-Bloom provides several opportunities for Duke Pharmacology graduate students and post-doctoral fellows to obtain experience in teaching.
- Ph.D., Georgetown University 1983
Sah, Renu, et al. “Modulation of the GABA(A)-gated chloride channel by reactive oxygen species..” Journal of Neurochemistry, vol. 80, no. 3, Feb. 2002, pp. 383–91. Epmc, doi:10.1046/j.0022-3042.2001.00706.x. Full Text
Schwartz-Bloom, R. D., et al. “Measurement of chloride movement in neuronal preparations..” Current Protocols in Neuroscience, vol. Chapter 7, May 2001. Epmc, doi:10.1002/0471142301.ns0710s04. Full Text
Schwartz-Bloom, R. D., and R. Sah. “gamma-Aminobutyric acid(A) neurotransmission and cerebral ischemia..” Journal of Neurochemistry, vol. 77, no. 2, Apr. 2001, pp. 353–71. Epmc, doi:10.1046/j.1471-4159.2001.00274.x. Full Text
Galeffi, F., et al. “Diazepam promotes ATP recovery and prevents cytochrome c release in hippocampal slices after in vitro ischemia..” Journal of Neurochemistry, vol. 75, no. 3, Sept. 2000, pp. 1242–49. Epmc, doi:10.1046/j.1471-4159.2000.0751242.x. Full Text
Schwartz-Bloom, R. D., and M. J. Halpin. “Integrating high school biology & chemistry using pharmacology topics relevant to high schoolers: A model curriculum..” Faseb Journal, vol. 14, no. 8, FEDERATION AMER SOC EXP BIOL, May 2000, pp. A1495–A1495.
Galeffi, F., and R. D. Schwartz-Bloom. “Diazepam promotes ATP recovery following oxygen-glucose deprivation in the hippocampal slice..” Faseb Journal, vol. 14, no. 8, FEDERATION AMER SOC EXP BIOL, May 2000, pp. A1500–A1500.
Schwartz-Bloom, R. D., et al. “Benzodiazepines protect hippocampal neurons from degeneration after transient cerebral ischemia: an ultrastructural study..” Neuroscience, vol. 98, no. 3, Jan. 2000, pp. 471–84. Epmc, doi:10.1016/s0306-4522(00)00144-5. Full Text
Sah, R., and R. D. Schwartz-Bloom. “Optical imaging reveals elevated intracellular chloride in hippocampal pyramidal neurons after oxidative stress..” The Journal of Neuroscience : The Official Journal of the Society for Neuroscience, vol. 19, no. 21, Nov. 1999, pp. 9209–17. Epmc, doi:10.1523/jneurosci.19-21-09209.1999. Full Text
Inglefield, J. R., and R. D. Schwartz-Bloom. “Fluorescence imaging of changes in intracellular chloride in living brain slices..” Methods (San Diego, Calif.), vol. 18, no. 2, June 1999, pp. 197–203. Epmc, doi:10.1006/meth.1999.0772. Full Text