Rochelle D. Schwartz-Bloom
Professor in Pharmacology & Cancer Biology
Dr. Schwartz-Bloom is a co-principal investigator for the National Science Foundation Phase II Noyce Fellowship program.
The Schwartz-Bloom laboratory has completed 18 years of research investigating novel pharmacologic approaches to prevent neuronal death caused by cerebral ischemia associated with cardiac arrest and stroke. The group studied how GABA neurotransmission dysfunction contributes to the death of hippocampal neurons after ischemia in vivo or in vitro. Dr. Schwartz-Bloom’s research program continues now exclusively in science education, which she started in 1996. With funds provided by the Duke Provost in 2007, Dr. Schwartz-Bloom established Duke Center for Science Education, an umbrella for all Duke-related activities in science education. She coordinates Duke faculty and student interests in curriculum development, research, and outreach activities in science education for the K-16 grades. Dr. Schwartz-Bloom also directs RISE (Raising Interest in Science Education, http://sites.duke.edu/rise), an office within the Department of Pharmacology and Cancer Biology, where she develops and provides novel science education curricular materials in the area of pharmacology to the K-12 and college community. One of the major programs that she developed is the Pharmacology Education Partnership (http://sites.duke.edu/thepepproject), a series of pharmacology- and drug abuse-related science education modules for high school biology and chemistry students. Testing of over 15,000 high school students has revealed that student performance in biology and chemistry improves when they use the pharmacology curriculum developed by her team. Dr. Schwartz-Bloom provides several opportunities for Duke Pharmacology graduate students and post-doctoral fellows to obtain experience in teaching.
- Ph.D., Georgetown University 1983
Sah, R, Galeffi, F, Ahrens, R, Jordan, G, and Schwartz-Bloom, RD. "Modulation of the GABA(A)-gated chloride channel by reactive oxygen species." J Neurochem 80.3 (February 2002): 383-391.
Schwartz-Bloom, RD, Engblom, AC, Akerman, KE, and Inglefield, JR. "Measurement of chloride movement in neuronal preparations." Curr Protoc Neurosci Chapter 7 (May 2001): Unit7.10-. Full Text
Schwartz-Bloom, RD, and Sah, R. "gamma-Aminobutyric acid(A) neurotransmission and cerebral ischemia." J Neurochem 77.2 (April 2001): 353-371. (Review)
Schwartz-Bloom, RD, and Sah, R. "γ-aminobutyric acid A neurotransmission and cerebral ischemia." Journal of Neurochemistry 77.2 (2001): 353-371. Full Text
Galeffi, F, Sinnar, S, and Schwartz-Bloom, RD. "Diazepam promotes ATP recovery and prevents cytochrome c release in hippocampal slices after in vitro ischemia." J Neurochem 75.3 (September 2000): 1242-1249.
Schwartz-Bloom, RD, and Halpin, MJ. "Integrating high school biology & chemistry using pharmacology topics relevant to high schoolers: A model curriculum." FASEB JOURNAL 14.8 (May 11, 2000): A1495-A1495.
Galeffi, F, and Schwartz-Bloom, RD. "Diazepam promotes ATP recovery following oxygen-glucose deprivation in the hippocampal slice." FASEB JOURNAL 14.8 (May 11, 2000): A1500-A1500.
Schwartz-Bloom, RD, Miller, KA, Evenson, DA, Crain, BJ, and Nadler, JV. "Benzodiazepines protect hippocampal neurons from degeneration after transient cerebral ischemia: an ultrastructural study." Neuroscience 98.3 (2000): 471-484.
Sah, R, and Schwartz-Bloom, RD. "Optical imaging reveals elevated intracellular chloride in hippocampal pyramidal neurons after oxidative stress." J Neurosci 19.21 (November 1, 1999): 9209-9217.