Rochelle D. Schwartz-Bloom

Rochelle D. Schwartz-Bloom

Professor Emeritus of Pharmacology & Cancer Biology

External address: 
B238 LSRC Building, Durham, NC 27710
Internal office address: 
Duke Box 3813, Durham, NC 27710
(919) 684-5181

Dr. Schwartz-Bloom is a co-principal investigator for the National Science Foundation Phase II Noyce Fellowship program.


The Schwartz-Bloom laboratory has completed 18 years of research investigating novel pharmacologic approaches to prevent neuronal death caused by cerebral ischemia associated with cardiac arrest and stroke. The group studied how GABA neurotransmission dysfunction contributes to the death of hippocampal neurons after ischemia in vivo or in vitro. Dr. Schwartz-Bloom’s research program continued in the area of science education, which she started in 1996.  Her science education research has included the development of novel science education curricular materials in the area of pharmacology to the K-12 and college community. One of the major programs that she developed is the Pharmacology Education Partnership (, a series of pharmacology- and drug abuse-related science education modules for high school biology and chemistry students. Testing of over 15,000 high school students has revealed that student performance in biology and chemistry improves when they use the pharmacology curriculum developed by her team.  All of Dr. Schwartz-Bloom's science education research activities are found on her website for Raising Interest in Science Education, or RISE  at  

With funds provided by the Duke Provost in 2007, Dr. Schwartz-Bloom also established the Duke Center for Science Education, an umbrella for all Duke-related activities in science education. The Center helps to coordinate Duke faculty and student interests in curriculum development, research, and outreach activities in science education for the K-16 grades.


  • Ph.D., Georgetown University 1983

Gabriel, E. M., et al. “Ischemic injury and extracellular amino acid accumulation in hippocampal area CA1 are not dependent upon an intact septo-hippocampal pathway.Brain Res, vol. 785, no. 2, Mar. 1998, pp. 279–86. Pubmed, doi:10.1016/s0006-8993(97)01415-7. Full Text

Inglefield, J. R., and R. D. Schwartz-Bloom. “Confocal imaging of intracellular chloride in living brain slices: measurement of GABAA receptor activity.J Neurosci Methods, vol. 75, no. 2, Aug. 1997, pp. 127–35. Pubmed, doi:10.1016/s0165-0270(97)00054-x. Full Text

Inglefield, J. R., et al. “Effect of transient cerebral ischemia on gamma-aminobutyric acidA receptor alpha 1-subunit-immunoreactive interneurons in the gerbil CA1 hippocampus.Hippocampus, vol. 7, no. 5, 1997, pp. 511–23. Pubmed, doi:10.1002/(SICI)1098-1063(1997)7:5<511::AID-HIPO7>3.0.CO;2-J. Full Text

Levin, E. D., et al. “Is binding to nicotinic acetylcholine and dopamine receptors related to working memory in rats?Brain Res Bull, vol. 43, no. 3, 1997, pp. 295–304. Pubmed, doi:10.1016/s0361-9230(97)00009-9. Full Text

Fubara, B. M., et al. “Distribution of GABAA, GABAB, and glycine receptors in the central auditory system of the big brown bat, Eptesicus fuscus.J Comp Neurol, vol. 369, no. 1, May 1996, pp. 83–92. Pubmed, doi:10.1002/(SICI)1096-9861(19960520)369:1<83::AID-CNE6>3.0.CO;2-G. Full Text

Schwartz-Bloom, R. D., et al. “Inhibition of GABA-gated chloride channels in brain by the arachidonic acid metabolite, thromboxane A2.Neuropharmacology, vol. 35, no. 9–10, 1996, pp. 1347–53. Pubmed, doi:10.1016/s0028-3908(96)00059-7. Full Text

Alicke, B., and R. D. Schwartz-Bloom. “Rapid down-regulation of GABAA receptors in the gerbil hippocampus following transient cerebral ischemia.J Neurochem, vol. 65, no. 6, Dec. 1995, pp. 2808–11. Pubmed, doi:10.1046/j.1471-4159.1995.65062808.x. Full Text

Schwartz, R. D., and X. Yu. “Optical imaging of intracellular chloride in living brain slices.J Neurosci Methods, vol. 62, no. 1–2, Nov. 1995, pp. 185–92. Pubmed, doi:10.1016/0165-0270(95)00075-5. Full Text

Schwartz, R. D., et al. “Diazepam, given postischemia, protects selectively vulnerable neurons in the rat hippocampus and striatum.J Neurosci, vol. 15, no. 1 Pt 2, Jan. 1995, pp. 529–39.