Rochelle D. Schwartz-Bloom
Professor in the Program in Education
Dr. Schwartz-Bloom is a co-principal investigator for the National Science Foundation Phase II Noyce Fellowship program.
The Schwartz-Bloom laboratory has completed 18 years of research investigating novel pharmacologic approaches to prevent neuronal death caused by cerebral ischemia associated with cardiac arrest and stroke. The group studied how GABA neurotransmission dysfunction contributes to the death of hippocampal neurons after ischemia in vivo or in vitro. Dr. Schwartz-Bloom’s research program continues now exclusively in science education, which she started in 1996. With funds provided by the Duke Provost in 2007, Dr. Schwartz-Bloom established Duke Center for Science Education, an umbrella for all Duke-related activities in science education. She coordinates Duke faculty and student interests in curriculum development, research, and outreach activities in science education for the K-16 grades. Dr. Schwartz-Bloom also directs RISE (Raising Interest in Science Education, http://sites.duke.edu/rise), an office within the Department of Pharmacology and Cancer Biology, where she develops and provides novel science education curricular materials in the area of pharmacology to the K-12 and college community. One of the major programs that she developed is the Pharmacology Education Partnership (http://sites.duke.edu/thepepproject), a series of pharmacology- and drug abuse-related science education modules for high school biology and chemistry students. Testing of over 15,000 high school students has revealed that student performance in biology and chemistry improves when they use the pharmacology curriculum developed by her team. Dr. Schwartz-Bloom provides several opportunities for Duke Pharmacology graduate students and post-doctoral fellows to obtain experience in teaching.
- Ph.D., Georgetown University 1983
"Erratum: Long-term neuroprotection by benzodiazepine full versus partial agonists after transient cerebral ischemia in the gerbil (Journal of Cerebral Blood Flow and Metabolism (May 1998) 18 (548-558))." Journal of Cerebral Blood Flow and Metabolism 18.7 (January 1, 1998): 817-null.
Inglefield, JR, and Schwartz-Bloom, RD. "Confocal imaging of intracellular chloride in living brain slices: measurement of GABAA receptor activity." J Neurosci Methods 75.2 (August 22, 1997): 127-135.
Inglefield, JR, Wilson, CA, and Schwartz-Bloom, RD. "Effect of transient cerebral ischemia on gamma-aminobutyric acidA receptor alpha 1-subunit-immunoreactive interneurons in the gerbil CA1 hippocampus." Hippocampus 7.5 (January 1997): 511-523. Full Text
Levin, ED, Torry, D, Christopher, NC, Yu, X, Einstein, G, and Schwartz-Bloom, RD. "Is binding to nicotinic acetylcholine and dopamine receptors related to working memory in rats?." Brain Res Bull 43.3 (1997): 295-304.
Fubara, BM, Casseday, JH, Covey, E, and Schwartz-Bloom, RD. "Distribution of GABAA, GABAB, and glycine receptors in the central auditory system of the big brown bat, Eptesicus fuscus." The Journal of Comparative Neurology 369.1 (May 1996): 83-92. Full Text
Schwartz-Bloom, RD, Cook, TA, and Yu, X. "Inhibition of GABA-gated chloride channels in brain by the arachidonic acid metabolite, thromboxane A2." Neuropharmacology 35.9-10 (1996): 1347-1353.
Alicke, B, and Schwartz-Bloom, RD. "Rapid down-regulation of GABAA receptors in the gerbil hippocampus following transient cerebral ischemia." J Neurochem 65.6 (December 1995): 2808-2811.
Schwartz, RD, and Yu, X. "Optical imaging of intracellular chloride in living brain slices." Journal of Neuroscience Methods 62.1-2 (November 1995): 185-192. Full Text
Schwartz, RD, Yu, X, Katzman, MR, Hayden-Hixson, DM, and Perry, JM. "Diazepam, given postischemia, protects selectively vulnerable neurons in the rat hippocampus and striatum." The Journal of Neuroscience : the Official Journal of the Society for Neuroscience 15.1 Pt 2 (January 1995): 529-539.
Inglefield, JR, Perry, JM, and Schwartz, RD. "Postischemic inhibition of GABA reuptake by tiagabine slows neuronal death in the gerbil hippocampus." Hippocampus 5.5 (January 1995): 460-468. Full Text